We solved TrkB,
a previously undruggable target

Over 30 years of scientific work and 34,000+ publications validate the target

Meet the team

Our experienced multidisciplinary international team includes the original inventors and qualified drug developers from the global pharmaceutical industry partnering with leading drug discovery CROs.

TEAM

Jami Mandelin

Co-founder, CEO
14 years of commercial & R&D experience from Faron Pharmaceuticals, Novartis, Roche
Georgios Trichas

Chief Business Officer
15 years of commercial experience from Achilles Therapeutics, Wellcome Trust
Matti Karvonen

Chief Medical Officer
20 years of drug development experience from Orion Pharma, Faron Pharmaceuticals, Roche, Biogen
Rafael Moliner

Co-founder, CSO
12 years of experience in TrkB biology from University of Helsinki
Peter Gallagher

Co-founder, Medicinal Chemistry Lead
36 years of medicinal chemistry experience in CNS drug discovery from Eli Lilly with 20+ patents
Tim Schulz-Utermoehl

DMPK Lead
23 years of neuroscience DMPK experience from MSD, AstraZeneca UK, Shire UK, Sygnature
Liz Mortimer-Cassen

Toxicology Lead
36 years of toxicology experience from AstraZeneca, Pfizer, Novo Nordisk, GSK, Evotec
Alan Harris

CMC Lead (DS)
45 years process chemistry experience from Fisons, Astra and AstraZeneca and CMC consultancy
Keith Purdy

CMC Lead (DP)
40 years in product development and CMC leadership roles at Boots, Fisons, Astra and AstraZeneca
Ali Lee

Head of IP
Chartered UK and EP Attorney with 25 years experience formerly at GSK
Satu Juhila

Research Program Director
16 years of drug research and development experience from Orion Pharma